Description

Threo-Guaiacylglycerol CAS NO 27391-16-8 is a specific stereoisomer of guaiacylglycerol, a key lignin-derived compound and a valuable chemical intermediate. This compound is significant for research and development in the fields of natural product chemistry, polymer science, and bio-based materials. It is primarily sought by industries and research institutions focused on sustainable chemistry, flavor and fragrance synthesis, and the study of lignin biodegradation pathways.

Application

• Lignin Model Compound Research: Serves as a crucial reference standard and building block for studying lignin structure, biosynthesis, and degradation mechanisms.
• Flavor & Fragrance Intermediate: Used in the synthesis of complex aroma chemicals and natural flavorants due to its guaiacyl (2-methoxyphenol) moiety.
• Bio-based Polymer Development: Acts as a renewable monomer or cross-linking agent for developing novel, sustainable polymers and resins.
• Phytochemical & Natural Product Synthesis: A key intermediate in the laboratory synthesis of various plant-derived polyphenols and bioactive compounds.
• Analytical Standard: Employed as a high-purity standard in chromatographic analysis (HPLC, GC) for quantifying lignin derivatives in environmental and industrial samples.
• Enzymology Studies: Used as a substrate to investigate the activity of enzymes like laccases and peroxidases involved in lignin modification.

Basic Information

Item	Detail
Product Name	Threo-Guaiacylglycerol
CAS No.	27391-16-8
Molecular Formula	C10H14O5
Molecular Weight	214.22 g/mol
Synonyms	1-(4-Hydroxy-3-methoxyphenyl)-1,2,3-propanetriol (threo-); Guaiacylglycerol-β-guaiacyl ether (threo-form); Erythro-Guaiacylglycerol β-Guaiacyl Ether (isomer); Threo-1-(4-Hydroxy-3-methoxyphenyl)glycerol; Lignin model compound; GGE (threo); β-O-4 Lignin Model Dimer (threo)
EINECS	Contact for details

Quality Control

Our Threo-Guaiacylglycerol is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC for assay and purity determination. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and research integrity requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity, the product should be stored under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.