Description

1H-Pyrazole-3-Carboxylic Acid, 5-Methyl-4-Nitro-, Methyl Ester is a high-value, functionalized pyrazole derivative serving as a critical synthetic intermediate. Its core value proposition lies in its versatile nitro and ester functional groups, which enable its use in constructing complex heterocyclic scaffolds for advanced research and development. This compound is primarily needed by pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry, crop protection, and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in developing kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Organic Synthesis & Research: A versatile precursor for further chemical transformations, including reduction, hydrolysis, and cross-coupling reactions in academic and industrial R&D labs.
• Material Science Precursor: Potential intermediate in the development of specialty polymers, ligands for catalysis, and organic electronic materials.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	1H-Pyrazole-3-Carboxylic Acid, 5-Methyl-4-Nitro-, Methyl Ester
CAS No.	27116-86-5
Molecular Formula	C6H7N3O4
Molecular Weight	185.14 g/mol
Synonyms	Methyl 5-methyl-4-nitro-1H-pyrazole-3-carboxylate; 5-Methyl-4-nitro-1H-pyrazole-3-carboxylic acid methyl ester; 4-Nitro-5-methyl-1H-pyrazole-3-carboxylic acid methyl ester; Methyl 4-nitro-5-methyl-1H-pyrazole-3-carboxylate; 1H-Pyrazole-3-carboxylic acid, 4-nitro-5-methyl-, methyl ester; 3-Carbomethoxy-5-methyl-4-nitropyrazole
EINECS	Contact for details

Quality Control

Our 1H-Pyrazole-3-Carboxylic Acid, 5-Methyl-4-Nitro-, Methyl Ester is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and ISO-aligned processes guarantees a reliable supply of high-purity material for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.