Description

Piperazine, 1-Methyl-4-(Trimethylsilyl)- (8Ci,9Ci) CAS NO 27001-68-9 is a specialized organosilicon derivative of piperazine, featuring a trimethylsilyl (TMS) protecting group. This compound is a valuable synthetic intermediate, prized for its role in modulating the reactivity and solubility of the piperazine core in advanced organic synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and fungicides where the piperazine moiety is required.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Acts as a monomer or modifier in the synthesis of specialty polymers with tailored thermal and mechanical properties.
• Organic Synthesis Reagent: Employed as a protecting group agent or a nucleophile in multi-step synthetic routes for complex natural products and fine chemicals.
• Chemical Research: Essential tool in academic and industrial R&D labs for exploring new chemical reactions and methodologies.

Basic Information

Product Name	Piperazine, 1-Methyl-4-(Trimethylsilyl)- (8Ci,9Ci)
CAS No.	27001-68-9
Molecular Formula	C8H20N2Si
Molecular Weight	172.35 g/mol
Synonyms	1-Methyl-4-(trimethylsilyl)piperazine; N-Methyl-4-(trimethylsilyl)piperazine; 4-(Trimethylsilyl)-1-methylpiperazine; 1-Methyl-4-trimethylsilylpiperazine; 27001-68-9; Piperazine, 1-methyl-4-(trimethylsilyl)-; (1-Methylpiperazin-4-yl)trimethylsilane
EINECS	Contact for details

Quality Control

Our Piperazine, 1-Methyl-4-(Trimethylsilyl)- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopy (NMR, IR), to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.