Description

2,2',4'-Trihydroxychalcone is a polyphenolic flavonoid derivative belonging to the chalcone class of organic compounds. This compound is valued for its role as a key synthetic intermediate and its potential bioactive properties, which are of significant interest in advanced research and development. It is primarily utilized by the pharmaceutical, nutraceutical, and fine chemical industries for applications in drug discovery, functional ingredient synthesis, and biochemical research.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of more complex flavonoid-based drugs and therapeutic agents.
• Biochemical Research: Used as a reference standard or probe in studies investigating antioxidant, anti-inflammatory, or enzyme inhibition mechanisms.
• Nutraceutical Development: Acts as a precursor for the development of high-value dietary supplements and functional food ingredients.
• Cosmetic Actives: Investigated for incorporation into skincare formulations for its potential antioxidant and skin-brightening properties.
• Organic Synthesis: Employed in academic and industrial laboratories for the construction of novel heterocyclic compounds and natural product analogs.
• Agrochemical Research: Explored as a lead compound for developing new plant growth regulators or protective agents.

Basic Information

Product Name	2,2',4'-Trihydroxychalcone
CAS No.	26962-50-5
Molecular Formula	C15H12O4
Molecular Weight	256.25 g/mol
Synonyms	2',4,4'-Trihydroxychalcone; 1-(2,4-Dihydroxyphenyl)-3-(2-hydroxyphenyl)-2-propen-1-one; 2,2',4'-Trihydroxy-1,3-diphenyl-2-propen-1-one; 2,4,2'-Trihydroxychalcone; NSC 407347; Butein (Note: Butein is a common name for this compound); (E)-1-(2,4-Dihydroxyphenyl)-3-(2-hydroxyphenyl)prop-2-en-1-one
EINECS	Contact for details

Quality Control

Our 2,2',4'-Trihydroxychalcone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets precise customer specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to brownish-yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	210 - 215 °C
Loss on Drying	≤ 2.0 %
Residue on Ignition	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.