Description

7-Chloro-4,6-Dimethoxy-6'-Methyl-2'-(1-Pyrrolidinyl)Spiro[Benzofuran-2(3H),1'-[2]Cyclohexene]-3,4'-Dione CAS NO 26881-66-3 is a complex spirocyclic organic compound featuring a benzofuran core fused with a cyclohexene-dione moiety. This specialized chemical serves as a high-value synthetic intermediate and a key scaffold for advanced research and development. It is primarily sought by pharmaceutical R&D and fine chemical synthesis teams for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or anti-infective targets.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and high-throughput screening libraries to discover new drug candidates.
• Organic Synthesis Reagent: Employed in advanced organic synthesis for constructing complex spirocyclic and heterocyclic compounds.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Agrochemical Research: Potential intermediate in the development of new generation herbicides or fungicides with novel modes of action.
• Material Science Precursor: Investigated for the synthesis of organic electronic materials or advanced polymers with specific optical properties.

Basic Information

Product Name	7-Chloro-4,6-Dimethoxy-6'-Methyl-2'-(1-Pyrrolidinyl)Spiro[Benzofuran-2(3H),1'-[2]Cyclohexene]-3,4'-Dione
CAS No.	26881-66-3
Molecular Formula	C21H22ClNO6
Molecular Weight	419.86 g/mol
Synonyms	7-Chloro-4,6-dimethoxy-6'-methyl-2'-(pyrrolidin-1-yl)spiro[benzofuran-2(3H),1'-cyclohex-2-ene]-3,4'-dione; Spiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione, 7-chloro-4,6-dimethoxy-6'-methyl-2'-(1-pyrrolidinyl)-; 26881-66-3; 7-Chloro-4,6-dimethoxy-6'-methyl-2'-(1-pyrrolidinyl)spiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione; Spirocyclic benzofuran-dione derivative.
EINECS	Contact for details

Quality Control

Our 7-Chloro-4,6-Dimethoxy-6'-Methyl-2'-(1-Pyrrolidinyl)Spiro[Benzofuran-2(3H),1'-[2]Cyclohexene]-3,4'-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR/MS for structural confirmation, to ensure compliance with exacting R&D and pharmaceutical intermediate standards. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.