Description

Methyl 2-Oxo-2-(Thiophen-2-Yl)Acetate is a high-purity organic building block and heterocyclic intermediate of significant importance in advanced chemical synthesis. Its core value lies in its reactive α-ketoester functionality adjacent to a thiophene ring, making it a versatile precursor for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the thiophene moiety can contribute to biological activity.
• Material Science Research: Serves as a monomer or precursor for synthesizing specialty polymers and organic electronic materials with unique conductive or optical properties.
• Chemical Research & Development: Employed in organic synthesis as a building block for heterocyclic compounds, ligands for catalysis, and in method development studies.
• Fine Chemical Production: Integral in the multi-step synthesis of complex flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	Methyl 2-Oxo-2-(Thiophen-2-Yl)Acetate
CAS No.	26878-13-7
Molecular Formula	C7H6O3S
Molecular Weight	170.19 g/mol
Synonyms	Methyl 2-oxo-2-(thiophen-2-yl)acetate; 2-Thiopheneglyoxylic acid methyl ester; Methyl (2-thienyl)oxoacetate; Methyl thiophene-2-glyoxylate; 2-Thienylglyoxylic acid methyl ester; Methyl 2-thienylglyoxylate; Oxo(2-thienyl)acetic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-Oxo-2-(Thiophen-2-Yl)Acetate is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure compliance with stringent purity specifications and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.