Description

(1R,2R)-2-Amino-Cyclohexanecarboxylic Acid Ethyl Ester is a high-purity chiral building block of significant importance in asymmetric synthesis. This compound matters as a key intermediate for constructing complex molecules with defined stereochemistry, enabling the development of pharmaceuticals and agrochemicals with high enantiomeric purity. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and neurological drug candidates.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides, where specific stereochemistry is essential for biological activity and environmental safety.
• Catalyst and Ligand Preparation: Serves as a precursor for chiral catalysts and ligands used in asymmetric hydrogenation and other enantioselective transformations.
• Peptidomimetics Research: Employed in medicinal chemistry for the design and synthesis of conformationally constrained peptide analogs to improve metabolic stability and bioavailability.
• Fine Chemical Production: A versatile building block for creating complex, high-value specialty chemicals with applications in materials science and diagnostics.

Basic Information

Product Name	(1R,2R)-2-Amino-Cyclohexanecarboxylic Acid Ethyl Ester
CAS No.	26849-62-7
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	Ethyl (1R,2R)-2-aminocyclohexanecarboxylate; (1R,2R)-2-Aminocyclohexanecarboxylic acid ethyl ester; L-2-Aminocyclohexanecarboxylic acid ethyl ester (trans-); trans-(1R,2R)-Ethyl 2-aminocyclohexanecarboxylate; (1R,2R)-ACCA-OEt; (1R,2R)-ACCA Ethyl Ester; Ethyl trans-2-aminocyclohexanecarboxylate (1R,2R)-; (1R,2R)-2-Amino-1-cyclohexanecarboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our (1R,2R)-2-Amino-Cyclohexanecarboxylic Acid Ethyl Ester is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with each batch to guarantee supply reliability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.