Description

Colestipol Hcl is a high-purity, pharmaceutical-grade anion exchange resin used as an active pharmaceutical ingredient (API). This compound is a critical component in the formulation of cholesterol-lowering medications, functioning as a bile acid sequestrant. It is primarily required by pharmaceutical manufacturers and research institutions developing treatments for hypercholesterolemia and related cardiovascular conditions.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription medications for lowering high blood cholesterol (hypercholesterolemia).
• Bile Acid Sequestrant: Binds bile acids in the intestine, preventing their reabsorption and promoting cholesterol excretion.
• Cardiovascular Drug Formulations: Used in solid oral dosage forms such as tablets and capsules designed for long-term cholesterol management.
• Clinical Research: Serves as a reference standard and key material in pharmacokinetic and efficacy studies for new lipid-regulating therapies.
• Drug Development: Utilized in pre-formulation studies, stability testing, and the development of generic pharmaceutical products.

Basic Information

Product Name	Colestipol Hydrochloride
CAS No.	26658-42-4
Molecular Formula	(C6H12ClN)n • xHCl
Molecular Weight	Contact for details
Synonyms	Colestipol Hydrochloride; Colestid; Lestid; Cholestabyl; Poly[N-(2-chloroethyl)-N-(2-hydroxyethyl)amine] hydrochloride; 1,2-Ethanediamine, N-(2-chloroethyl)-N-(2-hydroxyethyl)-, hydrochloride, polymer; DEAE-Sephadex derivative (hydrochloride form); Anion exchange resin (pharmaceutical grade)
EINECS	Contact for details

Quality Control

Our Colestipol Hcl is manufactured under strict quality systems to meet the rigorous standards of the pharmaceutical industry. Each batch is tested to ensure identity, purity, and performance as a bile acid sequestrant, with specifications aligned with major pharmacopoeial guidelines. A comprehensive Certificate of Analysis (COA) documenting all critical quality attributes is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect performance and stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Assay (on dried basis)	98.0% - 102.0%
Loss on Drying	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Chloride Content	Contact for details
Particle Size Distribution	Contact for details
Bile Acid Binding Capacity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.