Description

Ethyl 2-Methyl-4-(Trifluoromethyl)Furan-3-Carboxylate is a high-value fluorinated furan derivative, serving as a critical advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its molecular structure, featuring a trifluoromethyl group, imparts unique physicochemical properties that are essential for developing compounds with enhanced metabolic stability and bioavailability. This compound is primarily sought after by pharmaceutical R&D and fine chemical synthesis sectors for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS, anti-inflammatory, and antiviral applications.
• Agrochemical Synthesis: Used as a building block for developing advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental persistence.
• Material Science Precursor: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials due to its fluorine-containing aromatic system.
• Organic Synthesis Building Block: Facilitates various cross-coupling and functionalization reactions, enabling the construction of complex, fluorinated molecular architectures.
• Chemical Research & Development: Serves as a standard or starting material in academic and industrial labs for methodology development and exploration of furan chemistry.

Basic Information

Product Name	Ethyl 2-Methyl-4-(Trifluoromethyl)Furan-3-Carboxylate
CAS No.	26431-52-7
Molecular Formula	C9H9F3O3
Molecular Weight	222.16 g/mol
Synonyms	Ethyl 2-Methyl-4-(trifluoromethyl)-3-furancarboxylate; 3-Furancarboxylic acid, 2-methyl-4-(trifluoromethyl)-, ethyl ester; 2-Methyl-4-trifluoromethylfuran-3-carboxylic acid ethyl ester; 4-(Trifluoromethyl)-2-methylfuran-3-carboxylic Acid Ethyl Ester; Ethyl 2-Methyl-4-trifluoromethylfuran-3-carboxylate; Furan-3-carboxylic acid, 2-methyl-4-(trifluoromethyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our production of Ethyl 2-Methyl-4-(Trifluoromethyl)Furan-3-Carboxylate adheres to stringent quality management systems. Every batch is subjected to comprehensive analytical testing including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters such as assay and impurity profiles. We are committed to meeting the exacting standards required for GMP-grade intermediates and support regulatory filings with full traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.