Description

2-Deoxy-D-Arabino-Hexitol Pentakis(Trifluoroacetate) is a high-purity, fully protected derivative of a deoxy sugar alcohol, widely utilized as a critical synthetic intermediate in advanced organic and medicinal chemistry. Its primary value lies in its role as a versatile building block for the synthesis of complex carbohydrates, nucleosides, and glycoconjugates, where the trifluoroacetyl groups provide excellent protection for hydroxyl functionalities during multi-step reactions. This compound is essential for researchers and process chemists in the pharmaceutical, biotechnology, and fine chemical industries, particularly those developing novel therapeutics, diagnostic agents, and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of nucleoside analogs, antiviral agents, and other bioactive molecules.
• Glycochemistry Research: Used in the preparation of complex oligosaccharides, glycopeptides, and glycomimetics for drug discovery and biological studies.
• Carbohydrate Chemistry: Serves as a protected precursor for the generation of deoxy sugar derivatives and other modified carbohydrates.
• Bioconjugation: Facilitates the chemical modification of biomolecules for the development of targeted drug delivery systems and diagnostic probes.
• Process Chemistry: Employed in scale-up synthesis for the production of active pharmaceutical ingredients (APIs) and fine chemicals.
• Chemical Biology Tool: Used to probe biological processes involving carbohydrate recognition and metabolism.

Basic Information

Product Name	2-Deoxy-D-Arabino-Hexitol Pentakis(Trifluoroacetate)
CAS No.	26388-40-9
Molecular Formula	C16H15F15O11
Molecular Weight	656.27 g/mol
Synonyms	1,2,3,4,5-Penta-O-trifluoroacetyl-2-deoxy-D-arabino-hexitol; 2-Deoxy-D-arabino-hexitol penta(trifluoroacetate); D-Arabino-2-deoxyhexitol pentakis(trifluoroacetate); 2-Deoxy-D-glucose pentatrifluoroacetate derivative; Penta-O-trifluoroacetyl-2-deoxy-D-arabino-hexitol; 2-Deoxy-D-mannitol penta(trifluoroacetate) (stereoisomer); Fully protected 2-deoxyhexitol derivative
EINECS	Contact for details

Quality Control

Our 2-Deoxy-D-Arabino-Hexitol Pentakis(Trifluoroacetate) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.