Description

1,3-Dimethyl-2-Azidobenzene is a specialized aromatic azide compound with significant utility in synthetic organic chemistry. Its value lies in its role as a versatile precursor for click chemistry reactions and photolabile protecting groups, enabling efficient molecular assembly and functionalization. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors developing novel active ingredients and polymers.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly through Huisgen 1,3-dipolar cycloaddition (click chemistry) to create triazole linkages.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where its azide functionality allows for the introduction of heterocyclic systems.
• Polymer & Material Science: Serves as a cross-linking agent or functional monomer for creating advanced polymers with specific thermal or photochemical properties.
• Bioconjugation: Facilitates the labeling and modification of biomolecules (proteins, peptides, nucleic acids) for diagnostic and research applications.
• Photochemistry Research: Acts as a photolabile precursor, generating nitrenes upon UV irradiation for studies in reaction mechanisms and surface modification.
• Ligand & Catalyst Development: Employed in the synthesis of complex ligands and organometallic catalysts for asymmetric synthesis.

Basic Information

Product Name	1,3-Dimethyl-2-Azidobenzene
CAS No.	26334-20-3
Molecular Formula	C8H9N3
Molecular Weight	147.18 g/mol
Synonyms	2-Azido-1,3-dimethylbenzene; 2,6-Dimethylphenyl azide; 1-Azido-2,6-dimethylbenzene; o-Azidoxylene; Azidomesitylene (common misnomer); 2,6-Dimethylbenzenesulfonyl azide (precursor related); DNAN (context-specific abbreviation).
EINECS	Contact for details

Quality Control

Our 1,3-Dimethyl-2-Azidobenzene is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity, typically exceeding 97% (by HPLC). Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to cGMP principles where applicable, and our quality system is designed to meet the stringent requirements of pharmaceutical and advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at 2-8°C (refrigerated) or as specified on the label. Due to its highly volatile and easily oxidized nature, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Specific Impurity A	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.