Description

[(6-Bromohexyl)Oxy]Trimethylsilane is a versatile organosilicon compound featuring a reactive bromoalkyl chain protected by a trimethylsilyl (TMS) ether group. This bifunctional structure makes it a valuable intermediate for the synthesis of more complex molecules, particularly in advanced material science and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists working in organic synthesis, polymer modification, and surface functionalization.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, where the bromo group allows for further functionalization and the TMS group acts as a protecting group for alcohols.
• Polymer & Material Science: Serves as a key monomer or cross-linking agent for creating functionalized silicones, specialty polymers, and surface-modified inorganic materials like silica nanoparticles.
• Organic Synthesis Building Block: Employed in nucleophilic substitution reactions (SN2) to introduce hexyloxy chains or to create heterocyclic compounds and macrocycles.
• Liquid Crystal & OLED Material Precursor: Utilized in the production of advanced electronic materials, where its structure can be incorporated into mesogenic or charge-transporting molecules.
• Surface Modification Agent: Applied to modify the surface properties of metals, glass, or other substrates to impart hydrophobicity or specific chemical functionality.
• Cross-coupling Reactions: Acts as a substrate in various metal-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form carbon-carbon bonds.

Basic Information

Product Name	[(6-Bromohexyl)Oxy]Trimethylsilane
CAS No.	26306-00-3
Molecular Formula	C9H21BrOSi
Molecular Weight	253.25 g/mol
Synonyms	6-Bromohexyloxytrimethylsilane; Trimethyl(6-bromohexyloxy)silane; (6-Bromohexyloxy)trimethylsilane; 1-Bromo-6-(trimethylsilyloxy)hexane; Hexane, 1-bromo-6-(trimethylsilyloxy)-; O-[(6-Bromohexyl)]trimethylsilanol; TMS ether of 6-bromohexan-1-ol
EINECS	Contact for details

Quality Control

Our [(6-Bromohexyl)Oxy]Trimethylsilane is manufactured under strict quality protocols. Every batch undergoes rigorous analytical testing including GC, NMR, and titration to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality management system supports compliance with cGMP and ISO standards for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent hydrolysis of the silyl ether group. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.450 - 1.455
Density (g/mL at 20°C)	1.10 - 1.15

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.