Description

10-Iododecanoic Acid Trimethylsilyl Ester is a valuable organosilicon reagent and a protected form of a long-chain iodinated fatty acid. This compound is primarily used as a key synthetic intermediate in organic and medicinal chemistry research. It is particularly relevant for scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity building blocks for complex molecule synthesis.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly those targeting metabolic pathways or requiring lipophilic modifications.
• Agrochemical Synthesis: Used in the research and development of specialized pesticides and herbicides where the iodine atom and fatty acid chain provide unique biological activity.
• Material Science Research: Acts as a precursor for surface-modifying agents or monomers in the development of specialized polymers and coatings.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to form carbon-carbon bonds.
• Bioconjugation & Probe Development: Utilized in the creation of labeled fatty acids or other bioactive molecules for biochemical and diagnostic research.
• Organic Synthesis Reagent: Provides a protected carboxylic acid group (as the TMS ester) and a reactive iodine handle for multi-step synthetic sequences.

Basic Information

Product Name	10-Iododecanoic Acid Trimethylsilyl Ester
CAS No.	26305-96-4
Molecular Formula	C₁₃H₂₇IO₂Si
Molecular Weight	370.35 g/mol
Synonyms	10-Iododecanoic Acid TMS Ester; Trimethylsilyl 10-Iododecanoate; Decanoic Acid, 10-Iodo-, Trimethylsilyl Ester; TMS 10-Iododecanoate; 10-Iodo-decanoic Acid Trimethylsilyl Ester; (Trimethylsilyl) 10-Iododecanoate; 10-Iodocapric Acid Trimethylsilyl Ester
EINECS	Contact for details

Quality Control

Our 10-Iododecanoic Acid Trimethylsilyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FT-IR, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee it meets the rigorous standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area, away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.