Description

6-Iodohexanoic Acid Trimethylsilyl Ester is a valuable organosilicon-protected iodoalkanoic acid derivative, serving as a versatile bifunctional building block in advanced organic synthesis. Its structure combines a reactive alkyl iodide terminus with a silyl-protected carboxylic acid, enabling sequential and selective transformations under mild conditions. This compound is essential for researchers and process chemists in pharmaceutical development, agrochemical synthesis, and materials science, particularly for constructing complex molecules and functionalized polymers.

Application

• Pharmaceutical Intermediate: Key synthon for the preparation of active pharmaceutical ingredients (APIs), especially in carbon-carbon bond forming reactions like alkylations and cross-couplings.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators that require specific alkyl chain modifications.
• Polymer & Material Science: Serves as a functional monomer or chain-transfer agent for synthesizing specialty polymers with tailored properties, such as silicones or polyesters with pendant reactive groups.
• Organic Synthesis Reagent: Employed in nucleophilic substitution reactions and as a precursor for generating organometallic reagents (e.g., Grignard or organolithium species) for further elaboration.
• Bioconjugation & Probe Development: Useful for labeling biomolecules or modifying surfaces due to the reactive iodo group, which can participate in click chemistry or other bioconjugation strategies.
• Liquid Crystal & OLED Research: Acts as a building block for synthesizing mesogenic compounds or charge-transport materials used in display and lighting technologies.

Basic Information

Product Name	6-Iodohexanoic Acid Trimethylsilyl Ester
CAS No.	26305-95-3
Molecular Formula	C9H19IO2Si
Molecular Weight	314.24 g/mol
Synonyms	Trimethylsilyl 6-iodohexanoate; 6-Iodohexanoic Acid TMS Ester; Hexanoic acid, 6-iodo-, trimethylsilyl ester; TMS 6-Iodohexanoate; (6-Iodohexanoyloxy)trimethylsilane; Trimethyl(6-iodohexanoyloxy)silane; Silane, trimethyl(6-iodohexanoyloxy)-; 26305-95-3 (CAS)
EINECS	Contact for details

Quality Control

Our 6-Iodohexanoic Acid Trimethylsilyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and industrial use. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards where applicable, supporting its use in regulated development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its moisture-sensitive (hygroscopic) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Total impurities ≤ 3.0%
Density (at 20°C)	~1.25 g/cm³
Refractive Index (n20D)	~1.480

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.