Description

6-Chlorohexanoic Acid Trimethylsilyl Ester is a valuable organosilicon-protected intermediate, primarily used as a key building block in organic synthesis. Its trimethylsilyl (TMS) protecting group enhances stability and alters reactivity, making it crucial for controlled chemical transformations. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for synthesizing complex molecules and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring a protected carboxylic acid functionality.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the chloro and silyl ester groups serve as reactive handles.
• Polymer & Material Science: Serves as a monomer or functionalization agent for creating specialty polymers, silicones, and surface-modifying agents.
• Organic Synthesis Building Block: Employed in nucleophilic substitution reactions, chain elongation, and as a precursor to other functionalized hexanoic acid derivatives.
• Cross-Coupling Reactions: Acts as a substrate in various metal-catalyzed coupling reactions (e.g., Negishi, Kumada) to form carbon-carbon bonds.
• Liquid Crystal & OLED Material Research: Used in the development of advanced organic electronic materials due to its ability to modify solubility and electronic properties.

Basic Information

Product Name	6-Chlorohexanoic Acid Trimethylsilyl Ester
CAS No.	26305-94-2
Molecular Formula	C9H19ClO2Si
Molecular Weight	222.78 g/mol
Synonyms	Trimethylsilyl 6-chlorohexanoate; 6-Chlorohexanoic Acid TMS Ester; Hexanoic acid, 6-chloro-, trimethylsilyl ester; (6-Chlorohexanoyloxy)trimethylsilane; TMS 6-Chlorohexanoate; 6-Chloro-n-caproic Acid Trimethylsilyl Ester; NSC 163083
EINECS	Contact for details

Quality Control

Our 6-Chlorohexanoic Acid Trimethylsilyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis of the silyl ester group.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.