Description

1-Deoxy-L-Mannitol Pentakis(Trifluoroacetate) is a high-purity, fully protected derivative of L-mannitol, specifically designed for advanced synthetic applications. This compound is a critical intermediate in the synthesis of complex carbohydrates, nucleosides, and other bioactive molecules, offering superior reactivity and selectivity. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality building blocks for complex organic synthesis and process development.

Application

• Pharmaceutical Intermediate: A key protected synthon in the multi-step synthesis of novel drug candidates, particularly antiviral and anticancer agents.
• Carbohydrate Chemistry: Serves as a versatile starting material for the preparation of complex oligosaccharides, glycoconjugates, and glycomimetics.
• Nucleoside & Nucleotide Synthesis: Used in the preparation of modified nucleosides and their phosphoramidite derivatives for oligonucleotide therapeutics.
• Bioconjugation & Probe Development: Acts as a linker or scaffold for creating labeled probes and bioconjugates used in diagnostic assays and imaging.
• Process Chemistry & Scale-up: Employed in the development and optimization of scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Academic & Industrial Research: A valuable reagent for exploring new synthetic methodologies and investigating structure-activity relationships (SAR).

Basic Information

Product Name	1-Deoxy-L-Mannitol Pentakis(Trifluoroacetate)
CAS No.	26293-33-4
Molecular Formula	C16H11F15O11
Molecular Weight	628.24 g/mol
Synonyms	L-1,5-Anhydromannitol Pentakis(trifluoroacetate); 1,5-Anhydro-L-mannitol Penta(trifluoroacetate); 1,5-Anhydro-2,3,4,6-tetra-O-trifluoroacetyl-L-mannitol; Penta-O-trifluoroacetyl-1,5-anhydro-L-mannitol; 1,5-Anhydro-2,3,4,6-tetra-O-(trifluoroacetyl)-L-mannitol; Protected L-Mannitol Derivative; L-Mannitol Penta-Trifluoroacetate Ester
EINECS	Contact for details

Quality Control

Our 1-Deoxy-L-Mannitol Pentakis(Trifluoroacetate) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.