Description

Benzeneacetic Acid, A-Methoxy-A-(Trifluoromethyl)-, Methyl Ester, (S)- is a high-value chiral building block and intermediate in organic synthesis. This compound is significant for its trifluoromethyl and methoxy functional groups, which are key motifs in the development of advanced pharmaceuticals and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex, bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a trifluoromethylated stereogenic center.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the CF3 group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with unique electronic properties.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research focused on incorporating fluorine atoms into complex molecular architectures.

Basic Information

Product Name	Benzeneacetic Acid, A-Methoxy-A-(Trifluoromethyl)-, Methyl Ester, (S)-
CAS No.	26164-19-2
Molecular Formula	C11H11F3O3
Molecular Weight	248.20 g/mol
Synonyms	(S)-Methyl 2-Methoxy-2-(trifluoromethyl)phenylacetate; (S)-α-Methoxy-α-(trifluoromethyl)phenylacetic Acid Methyl Ester; Methyl (S)-(-)-MTPA; (S)-MTPA Methyl Ester; (S)-Mosher's Acid Methyl Ester; (S)-2-Methoxy-2-(trifluoromethyl)-2-phenylacetic Acid Methyl Ester; (S)-Methyl O-Methylmandelate, 3',3',3'-Trifluoro-
EINECS	Contact for details

Quality Control

Our Benzeneacetic Acid, A-Methoxy-A-(Trifluoromethyl)-, Methyl Ester, (S)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.