Description

2-Bromo-Isonicotinic Acid Methyl Ester is a versatile brominated pyridine derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a reactive halogen handle and a protected carboxylic acid group, enabling precise molecular construction for complex target molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and other heterocyclic-based therapeutic research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the pyridine core is a common bioactive motif.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials and functional polymers.
• Chemical Biology Probes: Useful for creating tagged molecules or probes for studying biological pathways and mechanisms.
• Custom Synthesis and Contract Manufacturing: A starting material for custom synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	2-Bromo-Isonicotinic Acid Methyl Ester
CAS No.	26156-48-9
Molecular Formula	C7H6BrNO2
Molecular Weight	216.03 g/mol
Synonyms	Methyl 2-Bromoisonicotinate; 2-Bromo-4-pyridinecarboxylic Acid Methyl Ester; Methyl 2-Bromo-4-pyridinecarboxylate; 2-Bromopyridine-4-carboxylic Acid Methyl Ester; Isonicotinic Acid, 2-Bromo-, Methyl Ester; 2-Bromoisonicotinic Acid Methyl Ester; 4-(Methoxycarbonyl)-2-bromopyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-Isonicotinic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.