Description

(+)-5-[(E)-1-[(4-Nitrobenzoyl)Oxy]-2-Butenyl]Tetrahydrofuran-2-One is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry and functionalized structure make it a valuable building block for creating complex, optically active molecules. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and other specialized organic compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially for compounds requiring specific stereochemical configurations.
• Asymmetric Synthesis: Used as a building block in stereoselective reactions to construct complex molecular architectures with high enantiomeric purity.
• Fine Chemical Production: Employed in the synthesis of specialty chemicals, agrochemicals, and advanced materials where precise molecular structure is critical.
• Academic & Industrial R&D: Serves as a valuable reagent in methodological development and exploratory chemistry within university and corporate research laboratories.
• Process Chemistry: Investigated for use in scalable synthetic routes during process development and optimization phases for new chemical entities.

Basic Information

Product Name	(+)-5-[(E)-1-[(4-Nitrobenzoyl)Oxy]-2-Butenyl]Tetrahydrofuran-2-One
CAS No.	26098-16-8
Molecular Formula	C15H15NO6
Molecular Weight	305.28 g/mol
Synonyms	(5R)-5-[(1E)-1-[(4-Nitrobenzoyl)oxy]but-1-en-2-yl]dihydrofuran-2(3H)-one; (R)-5-((E)-1-((4-Nitrobenzoyl)oxy)but-1-en-2-yl)dihydrofuran-2(3H)-one; (+)-5-[(E)-1-[(4-Nitrobenzoyl)oxy]-2-butenyl]tetrahydro-2-furanone; 26098-16-8; (R)-5-((E)-1-((4-Nitrobenzoyl)oxy)but-1-en-2-yl)tetrahydrofuran-2-one
EINECS	Contact for details

Quality Control

Our (+)-5-[(E)-1-[(4-Nitrobenzoyl)Oxy]-2-Butenyl]Tetrahydrofuran-2-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles. We are committed to meeting the stringent requirements of pharmaceutical R&D and advanced synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, we recommend maintaining the product at 2-8°C under an inert atmosphere to preserve stability and enantiomeric purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.