Description

Otilonium Bromide is a quaternary ammonium antimuscarinic agent with potent antispasmodic properties. This compound is a critical active pharmaceutical ingredient (API) valued for its targeted action on gastrointestinal smooth muscle. It is primarily utilized by pharmaceutical manufacturers in the development and production of prescription medications for functional gastrointestinal disorders. Otilonium Bromide CAS NO 26095-59-0 is supplied to meet the stringent quality requirements of the global pharmaceutical industry.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription drugs for treating irritable bowel syndrome (IBS) and other functional bowel disorders.
• Antispasmodic Formulations: Formulated into tablets, capsules, or other oral dosage forms designed to relieve abdominal pain, cramping, and bloating.
• Gastrointestinal Motility Research: Used as a reference standard or tool compound in pharmacological research and development focused on smooth muscle physiology.
• Analytical Reference Standard: Serves as a high-purity standard for quality control (QC) and analytical method development in pharmaceutical laboratories.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of finished dosage forms.
• Clinical Trial Material: Provided under GMP conditions for use in clinical studies evaluating new gastrointestinal therapies.

Basic Information

Product Name	Otilonium Bromide
CAS No.	26095-59-0
Molecular Formula	C29H41BrN2O3
Molecular Weight	545.56 g/mol
Synonyms	Otilonium Bromide; Spasmomen; (3-Diethylaminopropyl)-2,4,6-trimethylphenylammonium bromide dicarbamate; Dicetel; Otilonii Bromidum; Octylonium Bromide (common misnomer); N,N-Diethyl-N-methyl-3-[(2,4,6-trimethylphenyl)amino]-3-oxopropylammonium bromide carbamate
EINECS	Contact for details

Quality Control

Our Otilonium Bromide is manufactured and controlled under a quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and strength conform to established specifications, which are aligned with major pharmacopoeial standards. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in its original packaging until use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Microbial Limits	Meets Ph. Eur. requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.