Description

Boc-Asp(Obzl)-Onp is a protected amino acid derivative, specifically an active ester of Boc-aspartic acid β-benzyl ester. This compound is a critical building block in solid-phase peptide synthesis (SPPS), valued for its role in introducing aspartic acid residues while preventing unwanted side reactions. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel peptides, peptidomimetics, and therapeutic agents.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key protected and activated monomer for the controlled incorporation of aspartic acid.
• Pharmaceutical Research: For the synthesis of peptide-based drug candidates, hormones, and enzyme inhibitors.
• Bioconjugation: Used to create peptide-protein or peptide-small molecule conjugates for diagnostic and therapeutic applications.
• Material Science: In the development of peptide-modified surfaces, hydrogels, and biomaterials.
• Academic Research: A standard reagent in university and institutional labs for studying peptide structure, function, and synthesis methodologies.
• Custom Peptide Production: Employed by CROs and CDMOs for the contract manufacturing of complex, custom peptide sequences.

Basic Information

Product Name	Boc-Asp(Obzl)-Onp
CAS No.	26048-69-1
Molecular Formula	C23H26N2O7
Molecular Weight	442.47 g/mol
Synonyms	Boc-Asp(OBzl)-ONp; N-(tert-Butoxycarbonyl)-L-aspartic acid 4-benzyl ester 4-nitrophenyl ester; Boc-L-Aspartic acid β-benzyl ester p-nitrophenyl ester; (2S)-4-(Benzyloxy)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-oxobutanoic acid 4-nitrophenyl ester; Boc-Asp-OBzl-ONp; Boc-Asp(OBzl)-ONp; Boc-Asp(OBzl)-ONp ester; N-Boc-L-aspartic acid β-benzyl ester p-nitrophenyl ester
EINECS	Contact for details

Quality Control

Our Boc-Asp(Obzl)-Onp is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for sensitive research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation [α]	Contact for details
Water Content (KF)	≤0.5%
Single Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.