Description

5-Bromobenzofuran-2-Carboxylic Acid Methyl Ester is a high-purity brominated benzofuran derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its versatile reactivity, particularly in cross-coupling reactions and as a precursor for constructing complex heterocyclic scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in developing new generation herbicides, fungicides, and insecticides with novel modes of action.
• Material Science Precursor: Serves as a monomer or starting material for creating organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Synthesis: Utilized in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions to introduce the benzofuran moiety into more complex structures.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis and medicinal chemistry research within university and corporate laboratories.
• Ligand Synthesis: Can be hydrolyzed and further functionalized to create novel ligands for catalysis.

Basic Information

Product Name	5-Bromobenzofuran-2-Carboxylic Acid Methyl Ester
CAS No.	26028-36-4
Molecular Formula	C10H7BrO3
Molecular Weight	255.07 g/mol
Synonyms	Methyl 5-Bromobenzofuran-2-carboxylate; 5-Bromo-2-benzofurancarboxylic Acid Methyl Ester; 2-Benzofurancarboxylic acid, 5-bromo-, methyl ester; 5-Bromobenzofuran-2-methyl carboxylate; 26028-36-4; Methyl 5-bromo-1-benzofuran-2-carboxylate
EINECS	Contact for details

Quality Control

Our 5-Bromobenzofuran-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.