Description

(4-Acetyl-Phenyl)-Phosphonic Acid Diethyl Ester is a high-purity organophosphorus compound, specifically a phosphonic acid ester derivative, serving as a critical building block in advanced chemical synthesis. Its value lies in its bifunctional structure, featuring both a reactive acetyl group and a phosphonate moiety, which enables its use as a versatile intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing active ingredients and functional ligands.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting bone diseases or requiring phosphate bioisosteres.
• Agrochemical Synthesis: Building block for creating advanced herbicides, plant growth regulators, and other crop protection agents with enhanced activity.
• Ligand & Catalyst Development: Used to prepare specialized phosphonate-based ligands for metal catalysis and coordination chemistry.
• Material Science & Polymer Additives: Intermediate for flame retardants, stabilizers, and monomers that impart specific properties to polymers.
• Chemical Research & Development: A versatile reagent for organic synthesis, particularly in Horner-Wadsworth-Emmons (HWE) olefination reactions and cross-coupling methodologies.
• Surface Modification Agent: Potential use in creating self-assembled monolayers (SAMs) or for modifying material surfaces with specific functional groups.

Basic Information

Product Name	(4-Acetyl-Phenyl)-Phosphonic Acid Diethyl Ester
CAS No.	25944-71-2
Molecular Formula	C12H17O4P
Molecular Weight	256.23 g/mol
Synonyms	Diethyl (4-Acetylphenyl)phosphonate; 4-Acetylphenylphosphonic Acid Diethyl Ester; Diethyl P-(Acetylphenyl)phosphonate; (4-Acetylphenyl)phosphonic Acid Diethyl Ester; Phosphonic Acid, P-(4-Acetylphenyl)-, Diethyl Ester; Diethyl (4-Acetylbenzene)phosphonate
EINECS	Contact for details

Quality Control

Every batch of (4-Acetyl-Phenyl)-Phosphonic Acid Diethyl Ester is produced under strict quality management protocols. We employ advanced analytical techniques, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency meet the stringent requirements of our global B2B clients. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.