Description

1,2,3,4,6-Penta-o-Acetyl-D-Mannopyranose is a key acetylated sugar derivative, serving as a vital protected intermediate in synthetic carbohydrate chemistry. Its primary value lies in enabling the controlled synthesis of complex oligosaccharides, glycoconjugates, and other bioactive molecules by providing a reactive scaffold with defined stereochemistry. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries, particularly for developing novel therapeutics, diagnostic agents, and advanced materials.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of antiviral drugs, antibiotics, and complex glycosylated active pharmaceutical ingredients (APIs).
• Glycobiology Research: Used as a protected mannose donor in the enzymatic or chemical synthesis of oligosaccharides and glycoproteins for biological studies.
• Carbohydrate Chemistry: Serves as a versatile starting material for preparing other mannose derivatives, glycosides, and glycomimetics.
• Diagnostic Reagent Production: Employed in manufacturing labeled sugars and probes for diagnostic assays and imaging.
• Fine Chemical Synthesis: Intermediate in the production of specialty surfactants, chiral ligands, and other value-added chemicals.

Basic Information

Product Name	1,2,3,4,6-Penta-o-Acetyl-D-Mannopyranose
CAS No.	25941-03-1
Molecular Formula	C16H22O11
Molecular Weight	390.34 g/mol
Synonyms	Penta-O-acetyl-α-D-mannopyranose; α-D-Mannopyranose, 1,2,3,4,6-pentaacetate; 1,2,3,4,6-Penta-O-acetyl-α-D-mannose; Acetylated D-Mannose; Pentaacetylmannose; Mannose pentaacetate; α-Acetobromomannose precursor; Peracetylated D-mannose
EINECS	Contact for details

Quality Control

Our 1,2,3,4,6-Penta-o-Acetyl-D-Mannopyranose is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and synthesis. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support development under cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	108 - 112 °C
Specific Rotation [α]20/D	+48.0° to +52.0° (c=1 in CHCl3)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.