Description

Estradiol Benzoate is a potent, long-acting estrogen ester widely used in pharmaceutical formulations. This compound is valued for its enhanced stability and prolonged biological activity compared to unesterified estradiol, making it a critical active pharmaceutical ingredient (API). It is primarily utilized in the development and production of hormone replacement therapies (HRT), veterinary medicines, and specific oncology treatments. Global B2B buyers rely on a consistent supply of high-purity material to ensure the efficacy and safety of their final products.

Application

• Pharmaceutical API: Core ingredient in injectable hormone replacement therapies (HRT) for managing menopausal symptoms and hormonal deficiencies.
• Veterinary Pharmaceuticals: Used in estrus synchronization and fertility treatments in livestock and companion animals.
• Oncology Research: Employed in experimental studies and therapies related to hormone-sensitive cancers.
• Steroid Prodrug Development: Serves as a key intermediate in synthesizing more complex steroid-based pharmaceuticals.
• Reference Standard: Used in analytical laboratories for quality control and method validation (HPLC, GC).
• Biochemical Research: A tool compound for studying estrogen receptor (ER) signaling pathways in academic and R&D settings.

Basic Information

Product Name	Estradiol Benzoate
CAS No.	25918-98-3
Molecular Formula	C25H28O3
Molecular Weight	376.49 g/mol
Synonyms	Estradiol 3-Benzoate; 17β-Estradiol 3-benzoate; Benzoic acid, (17β)-estra-1,3,5(10)-triene-3,17-diol 3-ester; Estradiol monobenzoate; Benztrone; Dimenformon Benzoate; Follicyclin; Oestradiol Benzoate; Progynon-B
EINECS	247-356-5

Quality Control

Our Estradiol Benzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling, to ensure it meets stringent pharmaceutical-grade specifications. We provide full traceability and support compliance with major pharmacopoeial standards (e.g., USP, EP). Certificates of Analysis (COA) documenting purity, related substances, and residual solvents are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.