Description

Ethinylestradiol is a potent synthetic estrogen derivative, widely recognized for its high oral bioavailability and metabolic stability. This compound is a critical active pharmaceutical ingredient (API) essential for the formulation of numerous hormonal therapies. It is primarily required by pharmaceutical manufacturers and research institutions developing oral contraceptives, hormone replacement therapies, and treatments for specific endocrine disorders.

Application

• Pharmaceutical API: Primary active ingredient in combined oral contraceptive pills and hormone replacement therapy (HRT) medications.
• Hormonal Therapy: Used in the treatment of menopausal symptoms, hypogonadism, and certain types of prostate cancer.
• Veterinary Medicine: Employed in reproductive control and hormone therapy for animals.
• Biochemical Research: Serves as a reference standard and tool compound in endocrine, oncology, and reproductive biology research.
• Formulation Development: Key component in the R&D of novel drug delivery systems, including transdermal patches and implants.

Basic Information

Product Name	Ethinylestradiol
CAS No.	25918-91-6
Molecular Formula	C20H24O2
Molecular Weight	296.40 g/mol
Synonyms	Ethinyl Estradiol; 17α-Ethynylestradiol; EE2; 19-Nor-17α-pregna-1,3,5(10)-trien-20-yne-3,17-diol; Lynoral; Estinyl; Feminone; 17α-Ethynyl-1,3,5(10)-estratriene-3,17β-diol
EINECS	247-342-8

Quality Control

Our Ethinylestradiol is manufactured under strict quality management systems. It undergoes comprehensive analytical testing, including HPLC for assay and related substances, to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each batch to support regulatory compliance and customer quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Water (Karl Fischer)	≤ 1.0% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.