Description

21-Fluoro-16-Ethyl-19-Norprogesterone is a synthetic steroid derivative, specifically a fluorinated and alkylated analog of progesterone. This compound is of significant interest in pharmaceutical research and development due to its potential as a high-affinity ligand for steroid hormone receptors, offering a platform for creating novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of hormone-based therapies, diagnostic tools, and advanced biochemical studies.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel steroidal drugs targeting hormone-related conditions.
• Biochemical Research: Used as a reference standard or probe in studies investigating progesterone receptor (PR) binding affinity and function.
• Endocrinology Studies: Employed in preclinical research to explore the effects of fluorinated steroid analogs on metabolic and reproductive pathways.
• Drug Discovery: Acts as a core structure for medicinal chemistry programs aimed at developing new anti-inflammatory or hormonal agents with modified pharmacokinetic profiles.
• Academic Research: Utilized in university and institutional labs for advanced studies in organic synthesis and steroid chemistry.

Basic Information

Product Name	21-Fluoro-16-Ethyl-19-Norprogesterone
CAS No.	25908-76-3
Molecular Formula	C22H31FO2
Molecular Weight	346.48 g/mol
Synonyms	16α-Ethyl-21-fluoro-19-norpregn-4-ene-3,20-dione; 21-Fluoro-16α-ethyl-19-norprogesterone; 16-Ethyl-21-fluoro-19-norprogesterone; 16α-Ethyl-21-fluoro-19-norpregn-4-en-3,20-dione; Fluoroethylnorprogesterone; 25908-76-3; 16-Ethyl-21-fluoro-19-norpregn-4-ene-3,20-dione
EINECS	Contact for details

Quality Control

Our 21-Fluoro-16-Ethyl-19-Norprogesterone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.