Description

1-Hydroxy-8,8-Dimethyl-5-Oxobicyclo[2.2.2]Octane-2,3-Dicarboxylic Acid Dimethyl Ester is a high-purity, functionalized bicyclic compound that serves as a critical synthetic intermediate and building block in advanced organic chemistry. Its unique, rigid molecular framework and multiple reactive sites make it invaluable for constructing complex molecular architectures with precise stereochemistry. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty materials sectors seeking to develop novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those requiring complex, polycyclic core structures.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its functional groups for derivatization.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Specialty Polymer Monomer: Its rigid bicyclic structure can be incorporated into polymer backbones to enhance thermal stability and mechanical properties.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic synthesis, including cycloaddition and esterification reactions.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex fragrance and flavor molecules.

Basic Information

Item	Detail
Product Name	1-Hydroxy-8,8-Dimethyl-5-Oxobicyclo[2.2.2]Octane-2,3-Dicarboxylic Acid Dimethyl Ester
CAS No.	25864-66-8
Molecular Formula	C14H20O7
Molecular Weight	300.30 g/mol
Synonyms	Dimethyl 1-Hydroxy-8,8-dimethyl-5-oxobicyclo[2.2.2]octane-2,3-dicarboxylate; 5-Oxobicyclo[2.2.2]octane-2,3-dicarboxylic acid, 1-hydroxy-8,8-dimethyl-, dimethyl ester; Bicyclo[2.2.2]octane-2,3-dicarboxylic acid, 1-hydroxy-8,8-dimethyl-5-oxo-, dimethyl ester; 1-Hydroxy-8,8-dimethyl-5-oxobicyclo[2.2.2]octane-2,3-dicarboxylic acid dimethyl ester; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1-Hydroxy-8,8-Dimethyl-5-Oxobicyclo[2.2.2]Octane-2,3-Dicarboxylic Acid Dimethyl Ester is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for all critical parameters are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.