Description

Phenylmalonic Acid Monobenzyl Ester is a key protected intermediate in organic synthesis, valued for its role in constructing complex molecular architectures. Its primary importance lies in providing a versatile building block for pharmaceutical research and fine chemical manufacturing, where precise control over molecular structure is critical. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing malonate or phenylacetic acid derivatives.
• Peptidomimetic Synthesis: Used in the preparation of peptide analogs and enzyme inhibitors where the benzyl-protected acid group is required for selective coupling reactions.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, dyes, and performance materials.
• Academic and Industrial R&D: A valuable reagent for methodological development in organic chemistry and for exploring new reaction pathways.

Basic Information

Product Name	Phenylmalonic Acid Monobenzyl Ester
CAS No.	25774-02-1
Molecular Formula	C16H14O4
Molecular Weight	270.28 g/mol
Synonyms	Monobenzyl Phenylmalonate; Benzyl Hydrogen Phenylmalonate; Phenylmalonic Acid Benzyl Ester; 2-Benzyloxycarbonyl-2-phenylacetic Acid; (Benzyloxy)(phenyl)acetic Acid; α-Carboxy-α-phenylacetic Acid Benzyl Ester; Phenylmalonic Acid 1-Benzyl Ester
EINECS	Contact for details

Quality Control

Our Phenylmalonic Acid Monobenzyl Ester is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product should be kept under inert conditions where possible to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.