Description

2',7'-Dibromo-3',6'-Dihydroxyspiro[Isobenzofuran-1(3H),9'-[9H]Xanthene]-3-One is a high-purity, brominated xanthene derivative that serves as a critical synthetic intermediate and functional dye precursor. Its value lies in its unique spirocyclic structure and reactive bromine substituents, which enable precise chemical modifications for advanced material synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical, analytical chemistry, and specialty dye industries who require reliable, high-quality building blocks for developing novel compounds and sensors.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and diagnostic agents that leverage its fluorescent xanthene core.
• Fluorescent Probe & Sensor Development: Serves as a key precursor for creating advanced fluorescent dyes and molecular probes used in bioimaging and chemical detection.
• Organic Synthesis Building Block: The reactive bromine atoms make it a versatile intermediate for cross-coupling reactions (e.g., Suzuki, Sonogashira) to construct complex organic molecules.
• Material Science Research: Employed in the development of novel organic electronic materials, photochromic compounds, and light-harvesting arrays.
• Analytical Reagent: Can be utilized as a standard or reagent in chromatographic methods and spectroscopic analysis due to its distinct chemical signature.
• Dye & Pigment Manufacturing: Acts as a specialized intermediate for producing high-value, brominated xanthene-based dyes and colorants.

Basic Information

Product Name	2',7'-Dibromo-3',6'-Dihydroxyspiro[Isobenzofuran-1(3H),9'-[9H]Xanthene]-3-One
CAS No.	25709-81-3
Molecular Formula	C₂₀H₁₀Br₂O₅
Molecular Weight	490.10 g/mol
Synonyms	2',7'-Dibromospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3,3',6'-trione; Dibromospirofluorescein; 2',7'-Dibromofluorescein; 3',6'-Dibromofluoran; 2',7'-Dibromo-3',6'-dihydroxyfluoran; 2,7-Dibromofluorescein; CAS 25709-81-3
EINECS	Contact for details

Quality Control

Every batch of 2',7'-Dibromo-3',6'-Dihydroxyspiro[Isobenzofuran-1(3H),9'-[9H]Xanthene]-3-One is manufactured under a strict quality management system. We perform comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure the product meets exacting standards for research and industrial use. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.