Description

N,n-Bis(Trimethylsilyl)Glycine Methyl Ester is a specialized organosilicon-protected amino acid derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its dual role as a silylating agent and a protected glycine synthon, enabling complex peptide and heterocycle construction under mild conditions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where precise molecular assembly is paramount.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex peptides, peptidomimetics, and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators requiring specific amino acid motifs.
• Organosilicon Chemistry: Acts as a versatile silylating agent and precursor for silicon-containing compounds in material science.
• Peptide Coupling Reagent: Facilitates peptide bond formation in solid-phase and solution-phase peptide synthesis.
• Protecting Group Strategy: Provides temporary protection for the amino and carboxyl groups of glycine during multi-step synthetic sequences.
• Chemical Research & Development: A valuable tool for academic and industrial R&D in medicinal chemistry and synthetic methodology development.

Basic Information

Product Name	N,n-Bis(Trimethylsilyl)Glycine Methyl Ester
CAS No.	25688-73-7
Molecular Formula	C11H27NO2Si2
Molecular Weight	261.51 g/mol
Synonyms	Glycine, N,N-bis(trimethylsilyl)-, methyl ester; Methyl N,N-bis(trimethylsilyl)glycinate; BTMG Methyl Ester; Methyl 2-[bis(trimethylsilyl)amino]acetate; N,N-Bis(trimethylsilyl)glycine methyl ester; (Trimethylsilyl)amino-acetic acid methyl ester; N,N-Bis(TMS)glycine methyl ester; TMS-Gly-OMe
EINECS	Contact for details

Quality Control

Our N,n-Bis(Trimethylsilyl)Glycine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.