Description

1,3-Dioxolane-4-Carboxylicacid,2-Methyl-,Methylester,trans-()-(8Ci) is a specialized chiral building block and intermediate of significant interest in fine chemical synthesis. Its value lies in its unique dioxolane-protected carboxylic acid functionality, which is crucial for constructing complex molecules with precise stereochemistry. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and neurological drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer Chemistry: Acts as a monomer or modifying agent for creating specialty polymers with tailored properties, such as biodegradable plastics or functional coatings.
• Flavor and Fragrance Industry: Potential intermediate for synthesizing complex, naturally-derived flavor and aroma compounds.
• Academic and R&D: A valuable reagent for methodological studies in organic chemistry, particularly in reactions involving protected functional groups and stereoselective transformations.

Basic Information

Product Name	1,3-Dioxolane-4-Carboxylicacid,2-Methyl-,Methylester,trans-()-(8Ci)
CAS No.	25687-55-2
Molecular Formula	C7H10O5
Molecular Weight	174.15 g/mol
Synonyms	trans-Methyl 2-methyl-1,3-dioxolane-4-carboxylate; (4R,5S)-(-)-4-(Methoxycarbonyl)-2,2-dimethyl-1,3-dioxolane; Methyl (4R,5S)-(-)-2,2-dimethyl-1,3-dioxolane-4-carboxylate; (-)-Methyl 2,2-dimethyl-1,3-dioxolane-4(R)-carboxylate; (4R,5S)-4-Carbomethoxy-2,2-dimethyl-1,3-dioxolane; D-Glyceric acid methyl ester acetonide; (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolane-4-Carboxylicacid,2-Methyl-,Methylester,trans-()-(8Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.