Description

n-[(Benzyloxy)Carbonyl]-L-Glutamic Acid 5-Methyl 1-(Pentachlorophenyl) Ester is a sophisticated, high-purity protected amino acid derivative designed for advanced synthetic chemistry. This compound serves as a critical building block, enabling the controlled introduction of L-glutamic acid into complex molecular architectures. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require precise, reliable intermediates for peptide synthesis and the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key protected precursor in the solid-phase and solution-phase synthesis of therapeutic peptides and peptidomimetics.
• Bioconjugation Reagent: Used for the site-specific modification of proteins, antibodies, and other biomolecules in drug delivery and diagnostic applications.
• Organic Synthesis Building Block: Employed in multi-step organic syntheses to construct complex molecules for medicinal chemistry and chemical biology research.
• Protease Inhibitor Development: Acts as a core structural component in the design and synthesis of enzyme inhibitors targeting glutamic acid-specific proteases.
• Chemical Biology Probes: Utilized in the creation of activity-based probes and labeled compounds for studying biological pathways and mechanisms.

Basic Information

Product Name	n-[(Benzyloxy)Carbonyl]-L-Glutamic Acid 5-Methyl 1-(Pentachlorophenyl) Ester
CAS No.	25613-46-1
Molecular Formula	C20H18Cl5NO6
Molecular Weight	543.62 g/mol
Synonyms	Z-L-Glu(OMe)-OPcp; Cbz-L-Glutamic Acid 5-Methyl Ester 1-Pentachlorophenyl Ester; N-Carbobenzoxy-L-glutamic Acid α-Methyl γ-Pentachlorophenyl Ester; (S)-5-Methoxy-5-oxo-4-((((benzyloxy)carbonyl)amino)pentanoic acid pentachlorophenyl ester; L-Glutamic acid, N-[(phenylmethoxy)carbonyl]-, 5-methyl 1-(2,3,4,5,6-pentachlorophenyl) ester; Z-Glu(OMe)-OPcp Ester; Cbz-Glu(OMe)-OPcp
EINECS	Contact for details

Quality Control

Our production of n-[(Benzyloxy)Carbonyl]-L-Glutamic Acid 5-Methyl 1-(Pentachlorophenyl) Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and cGMP manufacturing. All materials are characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.