Description

Norgesterone is a synthetic progestin steroid, a key pharmaceutical intermediate and active pharmaceutical ingredient (API) in the development of hormonal therapies. Its precise molecular structure and high purity are critical for ensuring the efficacy and safety of final drug formulations. This compound is primarily utilized by pharmaceutical manufacturers and research institutions in the development of contraceptive and hormone replacement products.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of advanced progestogen-based active pharmaceutical ingredients (APIs).
• Hormone Replacement Therapy (HRT): Used in research and development of formulations for managing menopausal symptoms and hormonal imbalances.
• Contraceptive Development: A key component in the R&D of novel oral and implantable contraceptive agents.
• Endocrinology Research: Employed as a reference standard or tool compound in biochemical and pharmacological studies of progesterone receptors.
• Veterinary Pharmaceuticals: Applied in the development of hormonal treatments for reproductive management in animals.
• Analytical Standard: Used as a high-purity standard for quality control and method validation in analytical laboratories (HPLC, GC-MS).

Basic Information

Product Name	Norgesterone
CAS No.	25581-66-2
Molecular Formula	C₂₁H₂₈O₂
Molecular Weight	312.45 g/mol
Synonyms	17α-Ethynyl-18-methyl-19-nortestosterone; Ethynodiol; Ethynodiol diacetate (precursor); 17α-Ethynyl-18-methylestr-4-en-17β-ol-3-one; 13-Ethyl-17-hydroxy-18,19-dinor-17α-pregn-4-en-20-yn-3-one; Wy-3707; NSC-121698
EINECS	Contact for details

Quality Control

Our Norgesterone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting specifications suitable for pharmaceutical R&D and intermediate use. Certificates of Analysis (COA) detailing results for assay, related substances, and residual solvents are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.