Description

2,3-o-Isopropylidene-D-Erythronolactone is a high-purity chiral building block and protected lactone derivative of D-erythrose. This compound matters as a versatile and critical intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and fine chemical industries. It is primarily needed by research chemists and process development teams for the production of nucleoside analogs, antiviral agents, and other bioactive compounds where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the synthesis of nucleoside reverse transcriptase inhibitors and other antiviral drugs.
• Fine Chemical Synthesis: Building block for the preparation of complex natural products, sugars, and carbohydrate analogs.
• Asymmetric Catalysis Research: Used as a starting material or ligand precursor in the development of new catalytic systems.
• Agrochemical Development: Intermediate in the synthesis of novel, stereochemically-defined active ingredients.
• Academic & R&D Laboratories: Fundamental research tool in organic chemistry and medicinal chemistry for exploring new synthetic pathways.

Basic Information

Product Name	2,3-o-Isopropylidene-D-Erythronolactone
CAS No.	25581-41-3
Molecular Formula	C7H10O4
Molecular Weight	158.15 g/mol
Synonyms	D-erythrono-1,4-lactone 2,3-acetonide; (3aR,6R)-6-(Hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4(3aH)-one; 2,3-O-Isopropylidene-D-erythrono-1,4-lactone; D-Erythrono-1,4-lactone 2,3-O-isopropylidene; Isopropylidene-D-erythronolactone
EINECS	Contact for details

Quality Control

Our 2,3-o-Isopropylidene-D-Erythronolactone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and chiral integrity, meeting the stringent requirements of advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) and optical rotation values are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.