Description

(E)-2-Methyl-2-Butenoic Acid (1R)-2,3,5,7Aβ-Tetrahydro-7-[[[(E)-2-Methyl-1-Oxo-2-Butenyl]Oxy]Methyl]-1H-Pyrrolizin-1α-Yl Ester is a specialized organic ester with a complex molecular architecture, serving as a critical advanced intermediate in fine chemical synthesis. Its value lies in providing a unique pyrrolizine-based scaffold with reactive sites for further functionalization, enabling the development of novel compounds. This product is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries who require high-purity, structurally defined building blocks for complex molecule assembly.

Application

• Pharmaceutical Intermediate: A key chiral building block for the research and development of active pharmaceutical ingredients (APIs), particularly in exploring new therapeutic agents.
• Agrochemical Synthesis: Used in the synthesis of advanced crop protection agents and pesticides, leveraging its complex ester structure for biological activity.
• Chemical Research & Development: Serves as a sophisticated starting material or intermediate in academic and industrial R&D for novel organic compounds and materials science.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances where specific stereochemistry is required.
• Process Chemistry: Utilized in route scouting and optimization for the scalable production of complex target molecules in pilot plants.

Basic Information

Product Name	(E)-2-Methyl-2-Butenoic Acid (1R)-2,3,5,7Aβ-Tetrahydro-7-[[[(E)-2-Methyl-1-Oxo-2-Butenyl]Oxy]Methyl]-1H-Pyrrolizin-1α-Yl Ester
CAS No.	25471-38-9
Molecular Formula	C16H21NO4
Molecular Weight	291.34 g/mol
Synonyms	(1R)-2,3,5,7aβ-Tetrahydro-7-[[[(2E)-2-methyl-1-oxo-2-buten-1-yl]oxy]methyl]-1H-pyrrolizin-1α-yl (2E)-2-methyl-2-butenoate; 2-Butenoic acid, 2-methyl-, (1R,7aβ)-2,3,5,7a-tetrahydro-7-[[[(2E)-2-methyl-1-oxo-2-butenyl]oxy]methyl]-1H-pyrrolizin-1-yl ester; Tiglic Acid (1R)-2,3,5,7aβ-Tetrahydro-7-[[[(E)-2-Methyl-1-Oxo-2-Butenyl]Oxy]Methyl]-1H-Pyrrolizin-1α-Yl Ester; 25471-38-9; Pyrrolizine Ester Derivative; Advanced Chiral Ester Intermediate.
EINECS	Contact for details

Quality Control

Our production of (E)-2-Methyl-2-Butenoic Acid (1R)-2,3,5,7Aβ-Tetrahydro-7-[[[(E)-2-Methyl-1-Oxo-2-Butenyl]Oxy]Methyl]-1H-Pyrrolizin-1α-Yl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and specific test results are provided with every shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture and contamination. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.