Description

p-Methoxycinnamic Acid Trimethylsilyl Ester is a protected derivative of p-methoxycinnamic acid, where the carboxylic acid group is silylated to enhance stability and alter reactivity for synthetic transformations. This compound is a valuable intermediate and protecting group reagent in advanced organic synthesis, particularly in the production of pharmaceuticals and fine chemicals. It is primarily utilized by research institutions, pharmaceutical R&D labs, and specialty chemical manufacturers engaged in developing new active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of drug candidates, especially those containing cinnamic acid or chalcone scaffolds.
• Organic Synthesis Reagent: Used as a protected form of p-methoxycinnamic acid to prevent unwanted side reactions during multi-step synthesis.
• Fine Chemical Production: Intermediate in the manufacture of flavors, fragrances, and advanced materials requiring specific functional group manipulation.
• Academic & Industrial Research: Serves as a standard or starting material in methodological development and catalysis studies.
• UV-Absorbing Compound Precursor: Potential use in the development of organic UV filters or photostabilizers due to the cinnamate structure.

Basic Information

Product Name	p-Methoxycinnamic Acid Trimethylsilyl Ester
CAS No.	25436-23-1
Molecular Formula	C13H18O3Si
Molecular Weight	250.37 g/mol
Synonyms	(E)-3-(4-Methoxyphenyl)-2-propenoic acid trimethylsilyl ester; 4-Methoxycinnamic acid trimethylsilyl ester; Trimethylsilyl 4-methoxycinnamate; p-Methoxycinnamic acid TMS ester; TMS p-methoxycinnamate; (E)-Trimethylsilyl 3-(4-methoxyphenyl)acrylate; (2E)-3-(4-Methoxyphenyl)prop-2-enoic acid trimethylsilyl ester
EINECS	Contact for details

Quality Control

Our p-Methoxycinnamic Acid Trimethylsilyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request, supporting compliance with internal and regulatory standards for research and manufacturing use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.