Description

Ethyl 2-Oxopiperidine-4-Carboxylate is a versatile heterocyclic building block and ester derivative of nipecotic acid. This compound is of significant value in pharmaceutical research and fine chemical synthesis due to its functionalized piperidine scaffold. It is primarily sought after by R&D chemists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various pharmacologically active compounds, including potential central nervous system (CNS) agents, nootropics, and other bioactive molecules featuring a piperidine or piperidone core.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the 2-oxopiperidine structure imparts specific biological activity.
• Chemical Research & Development: Serves as a versatile building block for organic synthesis, enabling the construction of more complex heterocyclic systems and chiral molecules.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require high-purity, functionalized intermediates.
• Academic & Institutional Research: Utilized in universities and research institutes for methodological studies and the exploration of new synthetic pathways.

Basic Information

Product Name	Ethyl 2-Oxopiperidine-4-Carboxylate
CAS No.	25410-09-7
Molecular Formula	C8H13NO3
Molecular Weight	171.19 g/mol
Synonyms	Ethyl 2-oxo-4-piperidinecarboxylate; Ethyl 4-carboxy-2-piperidone; Ethyl 4-piperidone-2-carboxylate; 4-(Ethoxycarbonyl)-2-piperidone; 2-Piperidone-4-carboxylic acid ethyl ester; Ethyl nipecotate N-oxide derivative; NSC 163044
EINECS	Contact for details

Quality Control

Our Ethyl 2-Oxopiperidine-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay, related substances, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.