Description

n-[4-[[(2,4-Diamino-6-Pteridinyl)Methyl]Amino]Benzoyl]-L-Aspartic Acid is a high-purity biochemical intermediate of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block in the synthesis of complex molecules, particularly those targeting specific enzymatic pathways. It is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the development of novel therapeutic agents and biochemical probes. Our supply is characterized by stringent quality control to ensure batch-to-batch consistency for your most demanding applications.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel drug candidates, particularly in oncology and metabolic disease research.
• Biochemical Research: Used as a specialized reagent in enzymatic studies and the investigation of folate metabolism pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for constructing complex molecular architectures with specific biological activity.
• Academic Research: Utilized in university and institutional labs for fundamental studies in medicinal chemistry and chemical biology.

Basic Information

Product Name	n-[4-[[(2,4-Diamino-6-Pteridinyl)Methyl]Amino]Benzoyl]-L-Aspartic Acid
CAS No.	25312-31-6
Molecular Formula	C19H20N8O5
Molecular Weight	440.41 g/mol
Synonyms	L-Aspartic Acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]amino]benzoyl]-; 4-[[(2,4-Diaminopteridin-6-yl)methylamino]benzoyl]-L-aspartic acid; PT523; Dideazatetrahydrofolic Acid analog; NSC 127755; Pteroyl-L-aspartic acid derivative; Antifolate intermediate; (2S)-2-[[4-[[(2,4-Diaminopteridin-6-yl)methylamino]benzoyl]amino]butanedioic acid
EINECS	Contact for details

Quality Control

Our n-[4-[[(2,4-Diamino-6-Pteridinyl)Methyl]Amino]Benzoyl]-L-Aspartic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for research and development. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.