Description

4-Bromofluorescein is a halogenated derivative of fluorescein, a key xanthene dye. This compound is valued for its role as a versatile synthetic intermediate and a precursor for more complex fluorescent probes and labeling reagents. It is primarily utilized by research institutions and manufacturers in the life sciences, analytical chemistry, and specialty chemical sectors for developing diagnostic assays and advanced materials.

Application

• Fluorescent Probe Synthesis: Serves as a crucial intermediate for creating advanced fluorescent tags and sensors used in bioimaging and molecular biology.
• Bioconjugation & Labeling: Used to develop reactive derivatives for labeling proteins, antibodies, and nucleic acids in diagnostic kit manufacturing.
• Analytical Chemistry: Acts as a tracer or a standard in chromatographic methods (HPLC, TLC) and spectroscopic analysis.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized dyes for industrial and research applications.
• Photodynamic Therapy Research: Investigated as a potential photosensitizer precursor in medical and pharmaceutical research.
• Material Science: Used in the development of light-harvesting materials, OLEDs, and other photonic devices.

Basic Information

Product Name	4-Bromofluorescein
CAS No.	25109-80-2
Molecular Formula	C20H11BrO5
Molecular Weight	411.20 g/mol
Synonyms	4-Bromofluorescein; 2-(6-Bromo-3-oxo-3H-xanthen-9-yl)benzoic acid; 4-Bromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one; 4-Bromfluorescein; Bromofluorescein; Fluorescein, 4-bromo-; 4-Br-Fluorescein
EINECS	Contact for details

Quality Control

Our 4-Bromofluorescein is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.