Description

8-(Prop-2-Ynyl)-8-Azaspiro[4.5]Decane-7,9-Dione is a high-purity, specialized organic compound featuring a unique spirocyclic and alkyne-functionalized structure. This molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting neurological and metabolic disorders.
• Medicinal Chemistry Building Block: Used to introduce the spirocyclic and alkyne motifs into molecular scaffolds for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Research: Serves as a precursor in the synthesis of novel herbicides, fungicides, or plant growth regulators.
• Chemical Biology Probe Development: The alkyne group enables click chemistry applications for labeling and studying biological targets.
• Material Science Research: Potential monomer or cross-linker for developing specialty polymers with unique thermal or mechanical properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploratory synthesis projects.

Basic Information

Product Name	8-(Prop-2-Ynyl)-8-Azaspiro[4.5]Decane-7,9-Dione
CAS No.	25032-23-9
Molecular Formula	C13H15NO2
Molecular Weight	217.26 g/mol
Synonyms	8-(2-Propynyl)-8-azaspiro[4.5]decane-7,9-dione; 8-Propargyl-8-azaspiro[4.5]decane-7,9-dione; 7,9-Dioxo-8-(prop-2-yn-1-yl)-8-azaspiro[4.5]decane; 8-Azaspiro[4.5]decane-7,9-dione, 8-(2-propynyl)-; Spirocyclic Alkyne Dione; Propargyl Azaspirodecandione
EINECS	Contact for details

Quality Control

Our 8-(Prop-2-Ynyl)-8-Azaspiro[4.5]Decane-7,9-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support cGMP compliance for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. The container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.