Description

Trimethylsilyl Heptafluorobutyrate is a specialized organosilicon reagent featuring a perfluorinated butyrate ester group. This compound is valued for its role as a powerful derivatization agent in analytical chemistry, enhancing the volatility and detectability of target analytes. It is primarily sought by professionals in pharmaceutical research, environmental testing, and advanced material science for gas chromatography (GC) and mass spectrometry (MS) applications.

Application

• Analytical Derivatization: Used to silylate polar compounds (e.g., carboxylic acids, alcohols, amines) for improved separation and detection in GC and GC-MS analysis.
• Pharmaceutical Impurity Profiling: Employed in the analysis of drug metabolites and trace impurities due to its excellent derivatization efficiency.
• Environmental Analysis: Facilitates the detection and quantification of persistent organic pollutants, pesticides, and other environmental contaminants.
• Proteomics and Metabolomics: Serves as a derivatizing agent for complex biological samples to study metabolic pathways and protein modifications.
• Material Science Research: Acts as a precursor or surface-modifying agent in the synthesis of fluorinated silicon-based materials.
• Quality Control Laboratories: Utilized in the specification testing of raw materials and finished products where precise quantification of specific functional groups is required.

Basic Information

Product Name	Trimethylsilyl Heptafluorobutyrate
CAS No.	24929-99-5
Molecular Formula	C7H9F7O2Si
Molecular Weight	274.22 g/mol
Synonyms	Heptafluorobutyric Acid Trimethylsilyl Ester; Trimethylsilyl Perfluorobutanoate; TMS-HFB; (Perfluorobutyryloxy)trimethylsilane; Nonafluoro-1,1-dihydro-4-(trimethylsiloxy)butane; Trimethylsilyl 2,2,3,3,4,4,4-heptafluorobutanoate; 2,2,3,3,4,4,4-Heptafluorobutyric Acid Trimethylsilyl Ester
EINECS	Contact for details

Quality Control

Our Trimethylsilyl Heptafluorobutyrate is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for sensitive analytical applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material suitable for research and development under controlled conditions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere such as nitrogen or argon after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.