Description

2,4,6-Trimethylbenzenesulfonic Acid Azide is a specialized organic azide derivative of mesitylenesulfonic acid, serving as a versatile reagent in advanced synthetic chemistry. Its primary value lies in its role as a precursor for generating nitrenes under mild thermal or photochemical conditions, enabling key transformations such as C-H amination and aziridination. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries developing novel nitrogen-containing molecules and complex heterocycles.

Application

• Nitrene Precursor in Organic Synthesis: Used as a stable source of nitrenes for C-H bond functionalization and insertion reactions.
• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing nitrogen heterocycles.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and insecticides with unique modes of action.
• Polymer & Material Science: Facilitates cross-linking reactions and the introduction of functional groups into polymer backbones to modify material properties.
• Click Chemistry: Can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions under specific conditions for bioconjugation.
• Photochemical Applications: Utilized in photoaffinity labeling studies for probing biological interactions and protein binding sites.

Basic Information

Product Name	2,4,6-Trimethylbenzenesulfonic Acid Azide
CAS No.	24906-63-6
Molecular Formula	C9H11N3O3S
Molecular Weight	241.27 g/mol
Synonyms	Mesitylenesulfonyl Azide; Mesitylsulfonyl Azide; 2,4,6-Trimethylbenzenesulfonyl Azide; MesSO2N3; Azidotrimethylphenylsulfonate; Trimethylphenylsulfonyl Azide; Benzenesulfonic Acid, 2,4,6-Trimethyl-, Azide
EINECS	Contact for details

Quality Control

Our 2,4,6-Trimethylbenzenesulfonic Acid Azide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, moisture content, and solvent residues.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is strictly light-sensitive and easily oxidized; it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.