Description

1-Azidoadamantane 97 is a high-purity, functionalized adamantane derivative characterized by the presence of a reactive azide group. This compound matters as a versatile and valuable building block in advanced organic synthesis, enabling the introduction of the rigid, lipophilic adamantane scaffold via click chemistry and other azide-specific transformations. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapies, leveraging the adamantane moiety's biological activity.
• Click Chemistry Reagent: Used in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions to efficiently construct 1,2,3-triazole linkages, a cornerstone of bioconjugation and polymer chemistry.
• Material Science Building Block: Incorporated into polymers, dendrimers, and coatings to impart thermal stability, rigidity, and unique solubility characteristics.
• Agrochemical Research: Employed in the development of new pesticides and herbicides where the adamantane structure can enhance stability and bioavailability.
• Ligand and Catalyst Development: Acts as a scaffold for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• High-Energy Materials Research: Studied as a component in the design of novel propellants and explosives due to the energy-rich azide functional group.

Basic Information

Product Name	1-Azidoadamantane 97
CAS No.	24886-73-5
Molecular Formula	C10H15N3
Molecular Weight	177.25 g/mol
Synonyms	1-Azidoadamantane; 1-Adamantyl azide; Adamantane-1-azide; Azidotricyclo[3.3.1.13,7]decane; NSC 406916; Tricyclo[3.3.1.13,7]decane-1-azide; 1-Azidotricyclo[3.3.1.13,7]decane
EINECS	Contact for details

Quality Control

Our 1-Azidoadamantane 97 is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and assay. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled with care, avoiding exposure to strong heat, open flames, or reducing agents. For long-term storage, consider keeping under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.