Description

m-[Bis(2-Chloroethyl)Amino]Benzoic Acid Methyl Ester is a specialized nitrogen mustard derivative with significant utility as a key synthetic intermediate in advanced organic chemistry. This compound is valued for its bifunctional alkylating properties, enabling the synthesis of complex molecular architectures. It is primarily sought by research institutions and pharmaceutical development companies for applications in medicinal chemistry and the creation of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of nitrogen mustard-based chemotherapeutic agents and targeted cancer therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the development of novel alkylating agents for preclinical research.
• Bioconjugation: Serves as a linker or functionalizing agent for attaching cytotoxic payloads to antibodies, peptides, or other targeting molecules in ADC (Antibody-Drug Conjugate) development.
• Chemical Biology Probes: Employed in the design of molecular probes to study DNA alkylation, protein interactions, and cellular mechanisms.
• Polymer Chemistry: Can act as a monomer or cross-linking agent for creating specialty polymers with specific reactive or degradable properties.
• Agrochemical Synthesis: Intermediate in the development of certain herbicides and plant growth regulators that require specific alkylating functionalities.

Basic Information

Product Name	m-[Bis(2-Chloroethyl)Amino]Benzoic Acid Methyl Ester
CAS No.	24830-50-0
Molecular Formula	C₁₄H₁₉Cl₂NO₂
Molecular Weight	304.21 g/mol
Synonyms	Methyl 3-[bis(2-chloroethyl)amino]benzoate; 3-[Bis(2-chloroethyl)amino]benzoic acid methyl ester; NSC 176319; Benzoic acid, 3-[bis(2-chloroethyl)amino]-, methyl ester; m-[N,N-Bis(2-chloroethyl)amino]methyl benzoate; Methyl m-[bis(2-chloroethyl)amino]benzoate
EINECS	Contact for details

Quality Control

Our m-[Bis(2-Chloroethyl)Amino]Benzoic Acid Methyl Ester is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting research and development standards. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent batch-to-batch quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.