Description

m-[Bis(2-Chloroethyl)Amino]-N,n-Diisopropylbenzamide is a specialized nitrogen mustard derivative with a diisopropylbenzamide backbone, serving as a critical pharmaceutical intermediate and research chemical. Its molecular architecture, featuring the chloroethylamino functional group, makes it a valuable precursor in the synthesis of targeted therapeutic agents, particularly in oncology research. This compound is essential for medicinal chemists and process development teams in the pharmaceutical and biotechnology sectors who require high-purity building blocks for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the development of nitrogen mustard-based chemotherapeutic agents and targeted cancer therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of alkylating agents.
• Bioconjugation & Prodrug Synthesis: Serves as a linker or payload in the design of antibody-drug conjugates (ADCs) and other targeted drug delivery systems.
• Biochemical Tool Compound: Employed in laboratory research to study DNA alkylation mechanisms and cellular response to alkylating damage.
• Process Chemistry: Used in scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs) within GMP environments.
• Academic & Institutional Research: Fundamental compound for investigating novel anticancer mechanisms and developing next-generation therapeutics.

Basic Information

Product Name	m-[Bis(2-Chloroethyl)Amino]-N,n-Diisopropylbenzamide
CAS No.	24830-47-5
Molecular Formula	C₁₇H₂₆Cl₂N₂O
Molecular Weight	345.31 g/mol
Synonyms	N,N-Diisopropyl-3-[bis(2-chloroethyl)amino]benzamide; 3-[Bis(2-chloroethyl)amino]-N,N-diisopropylbenzamide; Benzamide, N,N-diisopropyl-3-[bis(2-chloroethyl)amino]-; m-[N,N-Bis(2-chloroethyl)amino]-N,N-diisopropylbenzamide; Nitrogen Mustard Benzamide Derivative; BCDB (abbrev.); 24830-47-5; 3-(Bis(2-chloroethyl)amino)-N,N-di(propan-2-yl)benzamide (IUPAC)
EINECS	Contact for details

Quality Control

Our m-[Bis(2-Chloroethyl)Amino]-N,n-Diisopropylbenzamide is manufactured under strict quality systems to ensure batch-to-batch consistency for critical research and development applications. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by HPLC, GC, NMR, and MS. Our quality commitment aligns with ICH guidelines for impurities and is suitable for use in non-GMP and GMP development phases upon agreement.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Store separately from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.