Description

Trimethyl Orthopropionate is a versatile orthoester compound widely used as a key building block and protecting group in organic synthesis. Its primary value lies in its ability to act as a propionylating agent and as a precursor for the synthesis of various heterocycles and complex molecules. This high-purity intermediate is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular construction is critical.

Application

• Pharmaceutical Intermediates: A crucial reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing propionate groups or constructing specific molecular frameworks.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, serving as a key precursor for active ingredients.
• Fine Chemical Manufacturing: Employed as a specialized building block for creating complex dyes, flavors, fragrances, and other high-value specialty chemicals.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Academic & Industrial R&D: A valuable tool for chemists in research laboratories for developing novel synthetic methodologies and exploring new chemical entities.
• Protecting Group Chemistry: Utilized to temporarily protect carboxylic acid or alcohol functionalities during multi-step synthetic sequences.

Basic Information

Product Name	Trimethyl Orthopropionate
CAS No.	24823-81-2
Molecular Formula	C6H14O3
Molecular Weight	134.17 g/mol
Synonyms	Trimethoxypropane; Propionic Acid Trimethyl Ester; Methyl Orthopropionate; Propane, 1,1,1-Trimethoxy-; Trimethyl Propane-1,1,1-triyl Trioxymethanide; Orthopropionic Acid Trimethyl Ester; 1,1,1-Trimethoxypropane
EINECS	246-461-5

Quality Control

Our Trimethyl Orthopropionate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive quality assurance, with each lot accompanied by a detailed Certificate of Analysis (COA) verifying key parameters such as identity, assay, and impurity profiles. Our commitment to reliable supply and technical support makes us a trusted partner for industrial-scale procurement.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.390 - 1.395
Density (20°C)	0.92 - 0.96 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.