Description

3-[Bis(2-Chloroethyl)Amino]-4-Methoxy-Benzoic Acid is a specialized nitrogen mustard derivative of benzoic acid, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring a bis(2-chloroethyl)amino group, makes it a valuable precursor for the development of targeted pharmaceutical agents and research compounds. This high-purity intermediate is essential for medicinal chemistry researchers and fine chemical manufacturers engaged in oncology drug discovery and the synthesis of biologically active molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the research and development of nitrogen mustard-based chemotherapeutic agents and targeted cancer therapies.
• Medicinal Chemistry Research: Used as a core scaffold for synthesizing novel compounds with potential alkylating activity for biological evaluation.
• Bioconjugation: Serves as a reactive handle for attaching cytotoxic payloads to antibodies, peptides, or other targeting ligands in Antibody-Drug Conjugate (ADC) research.
• Fine Chemical Synthesis: Intermediate in the multi-step synthesis of complex organic molecules requiring a functionalized benzoic acid core.
• Biochemical Tool Compound: Utilized in laboratory studies to investigate DNA alkylation mechanisms and cellular response pathways.
• Academic & Industrial R&D: Fundamental building block for universities and contract research organizations (CROs) exploring new chemical entities.

Basic Information

Product Name	3-[Bis(2-Chloroethyl)Amino]-4-Methoxy-Benzoic Acid
CAS No.	24812-96-2
Molecular Formula	C₁₄H₁₉Cl₂NO₃
Molecular Weight	320.21 g/mol
Synonyms	4-Methoxy-3-[bis(2-chloroethyl)amino]benzoic acid; NSC 82196; Benzoic acid, 4-methoxy-3-[bis(2-chloroethyl)amino]-; 3-[Bis(2-chloroethyl)amino]-4-methoxybenzoic acid; 4-Methoxy-3-[bis(2-chloroethyl)amino]benzoic acid; 3-(Bis(2-chloroethyl)amino)-4-methoxybenzoic acid; 3-[N,N-Bis(2-chloroethyl)amino]-4-methoxybenzoic acid
EINECS	Contact for details

Quality Control

Our 3-[Bis(2-Chloroethyl)Amino]-4-Methoxy-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.