Description

(25R)-3,3-(Ethylenebisoxy)-5α-Spirost-14-Ene CAS NO 24799-51-7 is a high-purity steroidal intermediate characterized by its specific spirostan structure with an ethylene ketal protecting group. This compound is a critical building block in the synthesis of complex steroid-based pharmaceuticals, offering a defined chiral center and functional group for targeted chemical modifications. It is essential for research and development chemists in the pharmaceutical and fine chemical industries working on novel therapeutic agents, particularly in the fields of hormone regulation and metabolic disease treatment.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the multi-step synthesis of advanced steroid-based active pharmaceutical ingredients (APIs).
• Steroid Hormone Research: Used as a foundational scaffold in medicinal chemistry for developing new analogs with potential therapeutic activity.
• Fine Chemical Synthesis: Employed in custom synthesis and process development for high-value, complex organic molecules.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Biochemical Research: Utilized in studies investigating steroid biosynthesis pathways and receptor interactions.

Basic Information

Product Name	(25R)-3,3-(Ethylenebisoxy)-5α-Spirost-14-Ene
CAS No.	24799-51-7
Molecular Formula	C29H44O4
Molecular Weight	456.66 g/mol
Synonyms	(25R)-Spirost-14-ene-3,3-diol, cyclic 3,3-ethylene acetal; 5α-Spirost-14-ene-3β,3β-diol, cyclic 3,3-(1,2-ethanediyl acetal), (25R)-; (25R)-3,3-Ethylenedioxy-5α-spirost-14-ene; 3,3-Ethylenedioxy-(25R)-5α-spirost-14-ene; Diosgenin ethylene ketal derivative; 14-Dehydrodiosgenin ethylene ketal; Steroid intermediate 24799-51-7
EINECS	Contact for details

Quality Control

Our (25R)-3,3-(Ethylenebisoxy)-5α-Spirost-14-Ene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.