Description

(20R,25R)-5α-Spirostane CAS NO 24799-49-3 is a high-purity, stereochemically defined spirostane derivative, a key structural motif in numerous bioactive natural products. This compound is valued for its role as a critical intermediate in the synthesis of steroidal pharmaceuticals and for advanced research in steroid chemistry. It is essential for R&D laboratories and production facilities in the pharmaceutical, agrochemical, and fine chemical sectors seeking a reliable building block for complex molecule synthesis.

Application

• Pharmaceutical Intermediate: A crucial chiral precursor for the synthesis of steroidal drugs, including certain hormones and cardiac glycosides.
• Research & Development: Used in academic and industrial research to study structure-activity relationships (SAR) and develop new steroidal compounds.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Fine Chemical Synthesis: Employed as a specialized building block in the multi-step synthesis of complex natural products and novel chemical entities.
• Agrochemical Research: Investigated for potential use in developing plant growth regulators or bioactive agents due to its steroidal backbone.

Basic Information

Product Name	(20R,25R)-5α-Spirostane
CAS No.	24799-49-3
Molecular Formula	C27H44O3
Molecular Weight	416.64 g/mol
Synonyms	(20R,25R)-5α-Spirostan-3β-ol; (20R,25R)-Spirostan-3β-ol; 5α-Spirostane, (20R,25R)-; (25R)-5α-Spirostan-3β-ol; Tigogenin (specific stereoisomer); Neotigogenin (related isomer); Spirostan-3-ol, (20R,25R)-5α-; 3β-Hydroxy-(20R,25R)-5α-spirostane
EINECS	Contact for details

Quality Control

Our (20R,25R)-5α-Spirostane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and identity confirmation via IR and NMR spectroscopy. We provide Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (20R,25R)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.